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- Top Stories of 2009: Editors' Choice
Gastroenterology Top Stories of 2009: Editors' Choice
SUMMARY AND COMMENT
CT Colonography for Colorectal Cancer Screening
- June 26, 2009
- Douglas K. Rex, MD
- Gastroenterology
Concerns remain about the procedure replacing colonoscopy as a colorectal cancer screening tool.
- Reviewing:
- Regge D et al. JAMA 2009 Jun 17; 301:2453
Finlayson E. JAMA 2009 Jun 17; 301:2498
SUMMARY AND COMMENT
Thiopurines and Risk for Lymphoproliferative Disorders
- November 6, 2009
- Douglas K. Rex, MD
- Gastroenterology
Patients with inflammatory bowel disease who received thiopurines had excess risk for LPDs.
- Reviewing:
- Beaugerie L et al. Lancet 2009 Oct 19
SUMMARY AND COMMENT
Genetic Variation and Treatment Response in Hepatitis C Patients
- October 16, 2009
- Atif Zaman, MD, MPH
- Gastroenterology
A genetic polymorphism helps explain why whites tend to have higher rates of response to HCV treatment than blacks.
- Reviewing:
- Ge D et al. Nature 2009 Sep 17; 461:399
SUMMARY AND COMMENT
PPIs and Clopidogrel: Data Trumps Fear
- October 16, 2009
- David A. Johnson, MD
- Gastroenterology
Antiplatelet function was diminished in PPI users, but cardiovascular outcomes were similar in PPI users and nonusers.
- Reviewing:
- O'Donoghue ML et al. Lancet 2009 Sep 19; 374:989
SUMMARY AND COMMENT
Water Infusion vs. Air Insufflation During Colonoscopy
- October 2, 2009
- Douglas K. Rex, MD
- Gastroenterology
Warm-water infusion was associated with fewer medication doses, better pain scores, and shorter recovery time.
- Reviewing:
- Leung JW et al. Gastrointest Endosc 2009 Sep; 70:505
SUMMARY AND COMMENT
Acid Symptoms After Proton-Pump–Inhibitor Discontinuation
- September 11, 2009
- David J. Bjorkman, MD, MSPH (HSA), SM (Epid.)
- Gastroenterology
Healthy volunteers developed acid-related symptoms after discontinuing a PPI that they had taken for 8 weeks.
- Reviewing:
- Reimer C et al. Gastroenterology 2009 Jul; 137:80
SUMMARY AND COMMENT
Are Proton-Pump Inhibitors Beneficial for Patients with Poorly Controlled Asthma?
- April 17, 2009
- Allan S. Brett, MD and David A. Johnson, MD
- Gastroenterology
For patients with minimal heartburn, probably not
- Reviewing:
- The American Lung Association Asthma Clinical Research Centers. N Engl J Med 2009 Apr 9; 360:1487
SUMMARY AND COMMENT
Wire-Guided vs. Conventional Cannulation of the Bile Duct
- July 17, 2009
- Stuart Sherman, MD
- Gastroenterology
Wire-guided cannulation was associated with lower rates of post–endoscopic retrograde cholangiopancreatography pancreatitis.
- Reviewing:
- Lee TH et al. Gastrointest Endosc 2009 Mar; 69:444
SUMMARY AND COMMENT
Should We Ablate Nondysplastic Barrett Esophagus?
- July 10, 2009
- David A. Johnson, MD
- Gastroenterology
In an opinion paper, experts disputed the reasons for using endoscopic ablation to reduce risk for cancer.
- Reviewing:
- Sharma P et al. Am J Gastroenterol 2009 Apr; 104:805
SUMMARY AND COMMENT
Radiofrequency Ablation Therapy for BE with Dysplasia
- May 27, 2009
- David A. Johnson, MD
- Gastroenterology
Radiofrequency ablation completely eradicated dysplasia and intestinal metaplasia in most patients and lowered risk for disease progression
- Reviewing:
- Shaheen NJ et al. N Engl J Med 2009 May 28; 360:2277
SUMMARY AND COMMENT
Split Dosing of Bowel Preparations
- April 24, 2009
- Douglas K. Rex, MD
- Gastroenterology
Shorter intervals between administration of cleansing agents and colonoscopies result in better-quality bowel preparations.
- Reviewing:
- Siddiqui AA et al. Gastrointest Endosc 2009 Mar; 69:700
SUMMARY AND COMMENT
More Data on Colonoscopy Withdrawal Time and Polyp Detection
- March 13, 2009
- Douglas K. Rex, MD
- Gastroenterology
Do longer withdrawal times actually improve detection rates, or are they simply markers for more-thorough mucosal examination?
- Reviewing:
- Sawhney MS et al. Gastroenterology 2008 Dec; 135:1892
