Gastroenterology: Archives

SUMMARY AND COMMENT

Variability of Liver Biopsy Assessment in Hepatitis C

• July 10, 2009
• Atif Zaman, MD, MPH

Hepatopathologists agreed with community pathologists’ fibrosis staging in approximately 50% of liver biopsy samples.

• Reviewing:
• Robert M et al., Clin Gastroenterol Hepatol 2009 Mar; 7:335

SUMMARY AND COMMENT

Cancer Risk from Inflammatory Bowel Disease

• July 2, 2009
• Douglas K. Rex, MD

Incidence of colorectal cancer did not change over time, although risk for CRC-related mortality declined.

• Reviewing:
• Söderlund S et al., Gastroenterology 2009 May; 136:1561

SUMMARY AND COMMENT

Mechanisms of Bloating in Irritable Bowel Syndrome

• July 2, 2009
• Douglas K. Rex, MD

The causes of anterior-wall protrusion differ in patients with dysmotility and functional intestinal disorder.

• Reviewing:
• Accarino A et al., Gastroenterology 2009 May; 136:1544

SUMMARY AND COMMENT

CT Colonography for Colorectal Cancer Screening

• June 26, 2009
• Douglas K. Rex, MD

Concerns remain about the procedure replacing colonoscopy as a colorectal cancer screening tool.

• Reviewing:
• Regge D et al., JAMA 2009 Jun 17; 301:2453 Finlayson E., JAMA 2009 Jun 17; 301:2498

SUMMARY AND COMMENT

Monitoring Asymptomatic Hepatitis B Patients

• June 19, 2009
• Atif Zaman, MD, MPH

Some patients at risk for alanine aminotransferase flares might benefit from being monitored every 3 months.

• Reviewing:
• Kumar M et al., Gastroenterology 2009 Apr; 136:1272

SUMMARY AND COMMENT

Blood Type and Nonvariceal Upper GI Bleeding

• June 19, 2009
• David J. Bjorkman, MD, MSPH (HSA), SM (Epid.)

An association between blood type O and nonvariceal upper gastrointestinal bleeding is not sufficient to imply causation.

• Reviewing:
• Bayan K et al., Dig Dis Sci 2009 May; 54:1029

SUMMARY AND COMMENT

Nitazoxanide for Genotype 4 Hepatitis C Virus Infection

• June 19, 2009
• Atif Zaman, MD, MPH

Triple therapy comprising nitazoxanide, peginterferon alfa-2a, and ribavirin increased the percentages of sustained virologic response in HCV patients compared with standard therapy. CME

• Reviewing:
• Rossignol J-F et al., Gastroenterology 2009 Mar; 136:856

SUMMARY AND COMMENT

Arterial Embolization for Bleeding Peptic Ulcers

• June 12, 2009
• David J. Bjorkman, MD, MSPH (HSA), SM (Epid.)

Coagulopathy and the use of coils alone for embolization are independently associated with rebleeding.

• Reviewing:
• Loffroy R et al., Clin Gastroenterol Hepatol 2009 May; 7:515

SUMMARY AND COMMENT

Terlipressin vs. Octreotide for Variceal Hemorrhage

• June 12, 2009
• Atif Zaman, MD, MPH

Terlipressin was not inferior to octreotide in controlling variceal hemorrhage, but it had no effect on in-hospital mortality. CME

• Reviewing:
• Abid S et al., Am J Gastroenterol 2009 Mar; 104:617

SUMMARY AND COMMENT

Hepatocellular Carcinomas in Patients with Metabolic Syndrome

• June 12, 2009
• Atif Zaman, MD, MPH

More patients with overt causes of liver disease had advanced fibrosis than patients with metabolic syndrome. CME

• Reviewing:
• Paradis V et al., Hepatology 2009 Mar; 49:851