Predicting Response to Hepatitis B Virus Therapy
SUMMARY AND COMMENT
Hepatitis B virus surface antigen levels during and after pegylated interferon alfa-2a therapy might be predictors of sustained virologic response.
CME
Reviewing:
Moucari R et al., Hepatology 2009 Apr; 49:1151
Brunetto MR et al., Hepatology 2009 Apr; 49:1141
Double-Balloon Enteroscopy for Obscure Gastrointestinal Bleeding
SUMMARY AND COMMENT
More than half of patients treated with DBE continued to bleed at 12 months.
Reviewing:
Gerson LB et al., Clin Gastroenterol Hepatol 2009 Jun; 7:664
Total Pancreatectomy for Chronic Pancreatitis
SUMMARY AND COMMENT
Concomitant islet cell transplantation reduced 24-hour insulin requirements.
CME
Reviewing:
Garcea G et al., Pancreas 2009 Jan; 38:1
Prevention of Aspirin-Associated Gastroduodenal Ulcers
SUMMARY AND COMMENT
Patients who received famotidine, a histamine-2–receptor antagonist, had lower risk for ulcers or erosive esophagitis than those who received placebo.
Reviewing:
Taha AS et al., Lancet 2009 Jul 11; 374:119
Antidepressants and Upper Gastrointestinal Bleeding
SUMMARY AND COMMENT
Risks for bleeding were increased with selective serotonin reuptake inhibitors but mitigated by proton-pump inhibitors.
Reviewing:
Targownik LE et al., Am J Gastroenterol 2009 Jun; 104:1475
Antioxidants for Pancreatitis-Related Abdominal Pain
SUMMARY AND COMMENT
Six months of therapy reduced pain and oxidative stress.
CME
Reviewing:
Bhardwaj P et al., Gastroenterology 2009 Jan; 136:149
Overuse and Underuse of Surveillance Colonoscopy
SUMMARY AND COMMENT
Low-risk patients might undergo too many colonoscopies; high-risk patients, too few.
CME
Reviewing:
Laiyemo AO et al., Clin Gastroenterol Hepatol 2009 May; 7:562
Capsule Endoscopy vs. Colonoscopy for Detecting Colonic Lesions
SUMMARY AND COMMENT
With colonoscopy as the standard of comparison, a new capsule endoscopy system adequately imaged the colon and rectum in 93% of patients.
Reviewing:
Van Gossum A et al., N Engl J Med 2009 Jul 16; 361:264
Wire-Guided vs. Conventional Cannulation of the Bile Duct
SUMMARY AND COMMENT
Wire-guided cannulation was associated with lower rates of post–endoscopic retrograde cholangiopancreatography pancreatitis.
Reviewing:
Lee TH et al., Gastrointest Endosc 2009 Mar; 69:444
Should We Ablate Nondysplastic Barrett Esophagus?
SUMMARY AND COMMENT
In an opinion paper, experts disputed the reasons for using endoscopic ablation to reduce risk for cancer.
CME
Reviewing:
Sharma P et al., Am J Gastroenterol 2009 Apr; 104:805