Incidence of Gastrointestinal Bleeding and Perforation
SUMMARY AND COMMENT
The gap between upper and lower GI complications is narrowing.
Reviewing:
Lanas A et al., Am J Gastroenterol 2009 Jul; 104:1633
Acid Symptoms After Proton-Pump–Inhibitor Discontinuation
SUMMARY AND COMMENT
Healthy volunteers developed acid-related symptoms after discontinuing a PPI that they had taken for 8 weeks.
CME
Reviewing:
Reimer C et al., Gastroenterology 2009 Jul; 137:80
Predicting Recurrent Adenomas
SUMMARY AND COMMENT
September 11, 2009
Douglas K. Rex, MD
Using results from baseline and surveillance colonoscopies provides better risk estimates than using results from the most recent examination alone.
CME
Reviewing:
Robertson DJ et al., Ann Intern Med 2009 Jul 21; 151:103
Compound Heterozygous Hemochromatosis: Long-Term Outcomes
SUMMARY AND COMMENT
People with C282Y/H63D mutations in the HFE gene were no more likely than people with neither mutation to develop hemochromatosis-related morbidity.
Reviewing:
Gurrin LC et al., Hepatology 2009 Jul; 50:94
Response to β-Blocker Therapy and Risk for Variceal Bleeding
SUMMARY AND COMMENT
Hemodynamic reduction of >10% from baseline reduces long-term risk for first variceal hemorrhage and ascites.
Reviewing:
Villanueva C et al., Gastroenterology 2009 Jul; 137:119
Predicting Extent of Gastric Intestinal Metaplasia
SUMMARY AND COMMENT
A new scoring system is not yet ready for prime time.
Reviewing:
de Vries AC et al., Gastrointest Endosc 2009 Jul; 70:18
Adenoma Detection: Morning vs. Afternoon
SUMMARY AND COMMENT
September 4, 2009
Douglas K. Rex, MD
Detection rates were significantly higher for colonoscopies performed in the morning than in the afternoon.
Reviewing:
Sanaka MR et al., Am J Gastroenterol 2009 Jul; 104:1659
Why Don't GI Docs Follow Surveillance Guidelines?
SUMMARY AND COMMENT
September 4, 2009
Douglas K. Rex, MD
Some weren't aware of the guidelines; others were but performed colonoscopies more often than recommended anyway.
Reviewing:
Saini SD et al., J Clin Gastroenterol 2009 Jul; 43:554
Aspirin Use After CRC Diagnosis Among Patients with COX-2–Expressing Tumors
SUMMARY AND COMMENT
September 4, 2009
Douglas K. Rex, MD
Taking aspirin was associated with lengthened survival in a subset of patients with colorectal cancer.
CME
Reviewing:
Chan AT et al., JAMA 2009 Aug 12; 302:649
Duodenal Cancer in Patients with Familial Adenomatous Polyposis
SUMMARY AND COMMENT
British polyposis registry data provide useful insights about cancer risk in patients with FAP.
Reviewing:
Latchford AR et al., Clin Gastroenterol Hepatol 2009 Jun; 7:659
