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Search for Dyspepsia in Gastroenterology
Physician-authored summaries on the latest research on dyspepsia, editorials on dyspepsia, and perspectives on dyspepsia - drawn from the top medical journals.
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You searched for: dyspepsia in Gastroenterology
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Predicting Response to Proton-Pump Inhibitors for Dyspepsia
- February 11, 2011
- David J. Bjorkman, MD, MSPH (HSA), SM (Epid.)
- Gastroenterology
The value of a therapeutic index to predict response is unclear.- Reviewing:
- Meineche-Schmidt V et al., Aliment Pharmacol Ther 2011 Jan; 33:41.
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What Is the Optimal Approach to Managing Dyspepsia?
- February 6, 2009
- David J. Bjorkman, MD, MSPH (HSA), SM (Epid.)
- Gastroenterology
In comparison studies, investigators found that two treatment schemes, the step-up approach and the test-and-treat approach, had the most benefits in the treatment of dyspepsia.- Reviewing:
- Duggan AE et al., Aliment Pharmacol Ther 2009 Jan; 29:55. van Marrewijk CJ et al., Lancet 2009 Jan 17; 373:215.
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Postprandial Symptoms in Functional Dyspepsia
- January 23, 2009
- David J. Bjorkman, MD, MSPH (HSA), SM (Epid.)
- Gastroenterology
Researchers found that postprandial fullness was the predominant symptom for dyspeptic patients whose symptoms are aggravated by meals, whereas pain was the predominant symptom for other dyspeptic patients.- Reviewing:
- Bisschops R et al., Gut 2008 Nov; 57:1495.
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Tegaserod for Dysmotility-Like Functional Dyspepsia
- October 30, 2008
- David J. Bjorkman, MD, MSPH (HSA), SM (Epid.)
- Gastroenterology
Tegaserod produced some symptomatic improvement in the symptoms of dysmotility-like functional dyspepsia, but the clinical significance of this improvement is unknown.- Reviewing:
- Vakil N et al., Am J Gastroenterol 2008 Aug; 103:1906.
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Test-and-Treat or PPI Therapy for Dyspepsia?
Researchers compared the cost-effectiveness of test-and-treat versus PPI acid-reduction strategies for dyspepsia.- Reviewing:
- Delaney BC et al., BMJ 2008 Mar 22; 336:651.
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Esomeprazole for Nonulcer Dyspepsia
- December 1, 2006
- David J. Bjorkman, MD, MSPH (HSA), SM (Epid.)
- Gastroenterology
Symptom relief was more common with 4 weeks of esomeprazole than with 4 weeks of placebo therapy.- Reviewing:
- van Zanten SV et al., Am J Gastroenterol 2006 Sep; 101:2096-106.
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Do Dyspepsia Symptoms Predict Pathophysiology?
Considerable overlaps of clinical and pathophysiologic features were found in patients with different predominant symptoms.- Reviewing:
- Karamanolis G et al., Gastroenterology 2006 Feb; 130:296-303.
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Symptom Scale for Dyspepsia
The Global Overall Symptom scale can identify overall symptom response to dyspepsia therapies in clinical trials.- Reviewing:
- Veldhuyzen van Zanten SJO et al., Aliment Pharmacol Ther 2006 Feb 15; 23:521-9.
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Test-and-Treat or Endoscopy for Dyspepsia?
- September 13, 2005
- David J. Bjorkman, MD, MSPH (HSA), SM (Epid.)
- Gastroenterology
In multiple studies, researchers have demonstrated a small beneficial effect of Helicobacter pylori eradication in patients with nonulcer dyspepsia. These findings have led to the . . .- Reviewing:
- Ford AC et al., Gastroenterology 2005 Jun; 128:1838-44.
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Age Threshold for Endoscopy in Dyspepsia
- September 13, 2005
- David J. Bjorkman, MD, MSPH (HSA), SM (Epid.)
- Gastroenterology
Results of multiple studies suggest that the most cost-effective approach to uninvestigated dyspepsia is to test for Helicobacter pylori and treat the infection, if present. . . .- Reviewing:
- Liou J-M et al., Gastrointest Endosc 2005 Jun; 61:819-25.
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Endoscopic Findings in Patients with Dyspepsia Free
In a community-based study, only one fourth of patients with dyspepsia had endoscopic findings.
CME Exam- Reviewing:
- Zagari RM et al., Am J Gastroenterol 2010 Mar; 105:565.
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Endoscopy for Evaluation of Dyspepsia
Endoscopy detected few malignant lesions but still might merit the cost in patients aged 50 or older.- Reviewing:
- Vakil N et al., Clin Gastroenterol Hepatol 2009 Jul; 7:756.
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Gastric Emptying and Meal-Related Symptoms of Dyspepsia
In healthy people, delays in gastric emptying did not induce dyspeptic symptoms.- Reviewing:
- Tack J et al., Aliment Pharmacol Ther 2006 Oct 1; 24:1045-50.
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Delayed Gastric Emptying Doesn’t Affect Quality of Life in Dyspeptic Patients Free
- September 29, 2006
- David J. Bjorkman, MD, MSPH (HSA), SM (Epid.)
- Gastroenterology
Identifying a common physiologic abnormality that affects quality of life is difficult, even in a population with similar symptoms.- Reviewing:
- Talley NJ et al., Gut 2006 Jul; 55:933-9.
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Helicobacter pylori Eradication and Body-Mass Index
BMI increased after eradication therapy, but the clinical significance is questionable.- Reviewing:
- Lane JA et al., Aliment Pharmacol Ther 2011 Apr; 33:922.
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A New Rapid Urease Test for H. pylori
- January 29, 2010
- David J. Bjorkman, MD, MSPH (HSA), SM (Epid.)
- Gastroenterology
Test sensitivity at 5 minutes was 94.5%.- Reviewing:
- Vaira D et al., Aliment Pharmacol Ther 2010 Jan 15; 31:331.
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Acid Symptoms After Proton-Pump–Inhibitor Discontinuation
- September 11, 2009
- David J. Bjorkman, MD, MSPH (HSA), SM (Epid.)
- Gastroenterology
Healthy volunteers developed acid-related symptoms after discontinuing a PPI that they had taken for 8 weeks.
CME Exam- Reviewing:
- Reimer C et al., Gastroenterology 2009 Jul; 137:80.
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Alarm Features for Upper Gastrointestinal Malignancy
- October 27, 2006
- David J. Bjorkman, MD, MSPH (HSA), SM (Epid.)
- Gastroenterology
Alarm symptoms probably have limited value in predicting UGI malignancy.- Reviewing:
- Vakil N et al., Gastroenterology 2006 Aug; 131:390-401.
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Gastrointestinal Tolerability of Nonselective NSAIDs and Valdecoxib
Nonsteroidal anti-inflammatory drug (NSAID) use is associated more often with moderate gastrointestinal symptoms than with the well-established severe complications of bleeding and symptomatic gastroduodenal ulcers. . . .- Reviewing:
- Eisen GM et al., Aliment Pharmacol Ther 2005 Mar 1; 21:591-8.
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Alarm Symptoms and Upper GI Malignancy
- March 16, 2005
- David J. Bjorkman, MD, MSPH, SM (Epid.)
- Gastroenterology
The appropriate approach for treating dyspepsia is controversial. Empirical therapy is often recommended for younger patients without alarm symptoms. To evaluate the diagnostic value of . . .- Reviewing:
- Fransen GA et al., Aliment Pharmacol Ther 2004 Nov 15; 20:1045-52.
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