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Search for H Pylori in Gastroenterology
Physician-authored summaries on the latest research on H. pylori, editorials on H. pylori, and perspectives on H. pylori - drawn from the top medical journals.
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You searched for: H. pylori in Gastroenterology
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Rabeprazole-Based Rescue Therapy for Helicobacter pylori Successful in Malaysia
After PPI-based triple therapy failed, most infections were eradicated with rabeprazole and amoxicillin.- Reviewing:
- Goh K-L et al., Aliment Pharmacol Ther 2012 May; 35:1097.
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Helicobacter pylori and Inflammatory Bowel Disease Free
- February 24, 2012
- David J. Bjorkman, MD, MSPH (HSA), SM (Epid.)
- Gastroenterology
Investigators conclude that H. pylori infection is inversely associated with IBD, whereas non–H. pylori chronic gastritis is positively associated with it.- Reviewing:
- Sonnenberg A and Genta RM., Aliment Pharmacol Ther 2012 Feb; 35:469.
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A New Four-Drug Regimen for H. pylori Infection?
- January 13, 2012
- David J. Bjorkman, MD, MSPH (HSA), SM (Epid.)
- Gastroenterology
Eradication was better than with standard triple therapy.- Reviewing:
- Basu PP et al., Am J Gastroenterol 2011 Nov; 106:1970.
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Sequential Therapy Bests Triple Therapy for H. pylori Infection
- January 13, 2012
- David J. Bjorkman, MD, MSPH (HSA), SM (Epid.)
- Gastroenterology
Eradication rates were higher; adverse events were similar.- Reviewing:
- Kim YS et al., Aliment Pharmacol Ther 2011 Nov; 34:1098.
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Can Celecoxib or Helicobacter pylori Eradication Reduce Gastric Lesions?
- November 4, 2011
- David J. Bjorkman, MD, MSPH (HSA), SM (Epid.)
- Gastroenterology
Regression of precancerous lesions was better with either treatment than with placebo.- Reviewing:
- Wong BCY et al., Gut 2011 Sep 13;:
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Helicobacter pylori Therapy in Latin America: Triple-Drug Regimen Still Best
Standard 14-day triple-drug therapy — despite its suboptimal eradication rate — was more effective than shorter-duration concomitant or sequential four-drug regimens.- Reviewing:
- Greenberg ER et al., Lancet 2011 Aug 6; 378:507. Mazzoleni LE et al., Lancet 2011 Aug 6; 378:462.
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Helicobacter pylori Eradication and Body-Mass Index
BMI increased after eradication therapy, but the clinical significance is questionable.- Reviewing:
- Lane JA et al., Aliment Pharmacol Ther 2011 Apr; 33:922.
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Quadruple Therapy for Helicobacter pylori Infection Free
A combination of bismuth subcitrate potassium, metronidazole, tetracycline, and omeprazole was safe and effective at eradicating H. pylori infection.
CME Exam- Reviewing:
- Malfertheiner P et al., Lancet 2011 Mar 12; 377:905.
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Helicobacter pylori Infection and Barrett Esophagus
- February 18, 2011
- David J. Bjorkman, MD, MSPH (HSA), SM (Epid.)
- Gastroenterology
H. pylori infection, chronic gastritis, and intestinal metaplasia were each inversely associated with Barrett esophageal metaplasia.- Reviewing:
- Sonnenberg A et al., Gastroenterology 2010 Dec; 139:1894.
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Does Helicobacter pylori Infection Increase Bleeding in Patients Taking Aspirin?
- October 15, 2010
- David J. Bjorkman, MD, MSPH (HSA), SM (Epid.)
- Gastroenterology
The research is still inconclusive.- Reviewing:
- Fletcher EH et al., Aliment Pharmacol Ther 2010 Oct; 32:831.
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Are Alarm Symptoms Predictive of Upper Gastrointestinal Cancer?
In a population in China with high prevalence of Helicobacter pylori infection, alarm symptoms were poor predictors of malignancy.- Reviewing:
- Bai Y et al., Gut 2010 Jun; 59:722.
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H. pylori Eradication in Patients with Gastric Lymphoma Free
Remission occurred in >75% of patients with early-stage, mucosa-associated lymphoid tissue (MALT) lymphoma.
CME Exam- Reviewing:
- Zullo A et al., Clin Gastroenterol Hepatol 2010 Feb; 8:105.
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Triple or Quadruple Therapy for Helicobacter pylori Infection?
Eradication rates were similar but suboptimal.
CME Exam- Reviewing:
- Luther J et al., Am J Gastroenterol 2010 Jan; 105:65.
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A New Rapid Urease Test for H. pylori
- January 29, 2010
- David J. Bjorkman, MD, MSPH (HSA), SM (Epid.)
- Gastroenterology
Test sensitivity at 5 minutes was 94.5%.- Reviewing:
- Vaira D et al., Aliment Pharmacol Ther 2010 Jan 15; 31:331.
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Early vs. Late H. pylori Eradication
- December 11, 2009
- David J. Bjorkman, MD, MSPH (HSA), SM (Epid.)
- Gastroenterology
Delaying treatment might increase risk for gastric cancer.
CME Exam- Reviewing:
- Wu C-Y et al., Gastroenterology 2009 Nov; 137:1641.
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H. pylori and Gastric Cancer
- October 30, 2009
- David J. Bjorkman, MD, MSPH (HSA), SM (Epid.)
- Gastroenterology
Eradication of H. pylori infection did not significantly reduce the incidence of gastric cancer.- Reviewing:
- Mabe K et al., World J Gastroenterol 2009 Sep 14; 15:4290.
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H. pylori Eradication and Risk for Gastric Cancer
Risk reduction was questionable in a meta-analysis of six studies.- Reviewing:
- Fuccio L et al., Ann Intern Med 2009 Jul 21; 151:121.
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Hyperglycemia Can Increase Risk for Gastric Cancer
Patients with both high HbA1c levels and Helicobacter pylori infection are at dramatically elevated risk.- Reviewing:
- Ikeda F et al., Gastroenterology 2009 Apr; 136:1234.
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Empirical Third-Line Therapy for Refractory H. pylori Infection
- February 13, 2009
- David J. Bjorkman, MD, MSPH (HSA), SM (Epid.)
- Gastroenterology
Use of an empirical levofloxacin-based third-line therapy, with no antibiotic-susceptibility testing, yielded high cumulative eradication rates.- Reviewing:
- Rokkas T et al., Am J Gastroenterol 2009 Jan; 104:21.
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What Is the Optimal Approach to Managing Dyspepsia?
- February 6, 2009
- David J. Bjorkman, MD, MSPH (HSA), SM (Epid.)
- Gastroenterology
In comparison studies, investigators found that two treatment schemes, the step-up approach and the test-and-treat approach, had the most benefits in the treatment of dyspepsia.- Reviewing:
- Duggan AE et al., Aliment Pharmacol Ther 2009 Jan; 29:55. van Marrewijk CJ et al., Lancet 2009 Jan 17; 373:215.
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