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Gastroenterology
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SUMMARY AND COMMENT
Is Endoscopic Surveillance of Gastric Ulcers Cost-Effective?Free
- July 30, 2010
- David J. Bjorkman, MD, MSPH (HSA), SM (Epid.)
Probably not, unless the prevalence of undetected malignancy exceeds 6%
- Reviewing:
- Yeh JM et al. Gastrointest Endosc 2010 Jul; 72:33
Recent Gastroenterology Articles
SUMMARY AND COMMENT
Is Acid-Reduction Therapy Associated with Risk for Hip Fractures?
- July 30, 2010
- David J. Bjorkman, MD, MSPH (HSA), SM (Epid.)
Another study adds to the confusion about this potential link.
- Reviewing:
- Corley DA et al. Gastroenterology 2010 Jul; 139:93
SUMMARY AND COMMENT
Self-Expanding Stents for Benign Esophageal Perforation
- July 30, 2010
- David A. Johnson, MD
Stents were effective, but which type to use remains unclear.
- Reviewing:
- van Heel NCM et al. Am J Gastroenterol 2010 Jul; 105:1515
SUMMARY AND COMMENT
An Antidepressant for Noncardiac Chest Pain?
- July 30, 2010
- David A. Johnson, MD
Symptoms improved significantly more with venlafaxine than with placebo.
- Reviewing:
- Lee H et al. Am J Gastroenterol 2010 Jul; 105:1504
SUMMARY AND COMMENT
U.S. Colorectal Cancer Screening: An Update
- July 30, 2010
- Douglas K. Rex, MD
CDC data from 2008 reveal a positive trend in the CRC screening rate but also areas in which improvement is warranted.
- Reviewing:
- Centers for Disease Control and Prevention (CDC). MMWR Morb Mortal Wkly Rep 2010 Jul 9; 59:808
SUMMARY AND COMMENT
A Combined Antegrade–Retrograde Approach to Esophageal Dilation
- July 23, 2010
- David A. Johnson, MD
When an otolaryngologist and a gastroenterologist rendezvous, patients with radiation-induced strictures have a strong chance at achieving dilation.
- Reviewing:
- Dellon ES et al. Gastrointest Endosc 2010 Jun; 71:1122
SUMMARY AND COMMENT
Are Alarm Symptoms Predictive of Upper Gastrointestinal Cancer?
- July 23, 2010
- David J. Bjorkman, MD, MSPH (HSA), SM (Epid.)
In a population in China with high prevalence of Helicobacter pylori infection, alarm symptoms were poor predictors of malignancy.
- Reviewing:
- Bai Y et al. Gut 2010 Jun; 59:722
SUMMARY AND COMMENT
Probiotics to Reduce Nonsteroidal Anti-Inflammatory Enteropathy?
- July 23, 2010
- David J. Bjorkman, MD, MSPH (HSA), SM (Epid.)
In a small crossover trial, a probiotic mixture reduced fecal calprotectin concentrations in healthy volunteers who were receiving indomethacin.
- Reviewing:
- Montalto M et al. Aliment Pharmacol Ther 2010 Jul; 32:209
SUMMARY AND COMMENT
Redefining Pancreatitis After Endoscopic Retrograde Cholangiopancreatography
- July 23, 2010
- Stuart Sherman, MD
The clinical and expert consensus definitions of post-ERCP pancreatitis do not correlate well.
- Reviewing:
- Artifon ELA et al. Pancreas 2010 May; 39:530
SUMMARY AND COMMENT
Endoscopic Ultrasound Diagnosis of Chronic Pancreatitis
- July 23, 2010
- Stuart Sherman, MD
Interobserver agreement with the Rosemont scoring system was modestly better than that with standard scoring but not significantly so.
- Reviewing:
- Stevens T et al. Gastrointest Endosc 2010 Mar; 71:519
SUMMARY AND COMMENT
Capsule Endoscopy for Obscure Gastrointestinal Bleeding?
- July 16, 2010
- David J. Bjorkman, MD, MSPH (HSA), SM (Epid.)
Capsule endoscopy bested small-bowel radiography in terms of diagnostic yield — but not clinical outcomes — in a randomized trial.
- Reviewing:
- Laine L et al. Gastroenterology 2010 May; 138:1673
Editor's Picks from across Journal Watch
SUMMARY AND COMMENT
Comparing Gastrointestinal Risks of Various Drugs
- June 10, 2010
- By Allan S. Brett, MD
- General Medicine
Certain nonsteroidal anti-inflammatory drugs, namely cyclooxygenase-2 inhibitors and ibuprofen, conferred lower risks than others in the class.
- Reviewing:
- Arthritis Rheum 2010 Jun; 62:1592
SUMMARY AND COMMENT
Promising New Drug for Hepatitis C Infection
- May 20, 2010
- By Anthony L. Komaroff, MD
- General Medicine
A single dose of a novel compound led to sustained virologic suppression. CME
- Reviewing:
- Nature 2010 May 6; 465:96
SUMMARY AND COMMENT
Angiotensin-Receptor Blockers and Cancer: An Inconvenient Truth?Free
- June 13, 2010
- By Harlan M. Krumholz, MD, SM
- Cardiology
A meta-analysis fuels uncertainty about safety, highlighting an imperative need for more data. CME
- Reviewing:
- Lancet 2010 Jun 14
NEWS IN CONTEXT
Denosumab Approved for Osteoporosis
- June 10, 2010
- By Andrew M. Kaunitz, MD
- Women's Health
Antibody suppresses bone turnover, thereby lowering fracture incidence; cost could be a concern.
- Reviewing:
- 2010 Jun 1
Journal Watch Gastroenterology summarizes important medical journal articles about a wide variety of GI subjects including cirrhosis, dyspepsia, gastric cancer, GERD, H. pylori, and hepatitis.
