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Gastroenterology
Journal Watch condenses summaries of key research across specialties from more than 250 medical journals into concise yet comprehensive articles, incorporating clinical commentary from prominent physician-editors in the field.
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Featured Article
SUMMARY AND COMMENT
Laxative-Free CT Colonography: Still Not Good Enough
- May 18, 2012
- Douglas K. Rex, MD
The positive predictive value was low — particularly for polyps smaller than 10 mm.
- Reviewing:
- Zalis ME et al. Ann Intern Med 2012 May 15; 156:692
Recent Gastroenterology Articles
SUMMARY AND COMMENT
Radiofrequency Ablation Is Locally Curative for Hepatocellular Carcinoma
- May 18, 2012
- Atif Zaman, MD, MPH
Also, 5-year survival was similar for RFA and surgical resection in select patients.
- Reviewing:
- Shiina S et al. Am J Gastroenterol 2012 Apr; 107:569
SUMMARY AND COMMENT
Cancer Risk Increased in Relatives of Patients with Serrated Polyposis
- May 11, 2012
- Douglas K. Rex, MD
Findings support evidence for an inherited component to the disease.
- Reviewing:
- Win AK et al. Am J Gastroenterol 2012 May; 107:770
SUMMARY AND COMMENT
A Review of Drug Interactions of Telaprevir and Boceprevir
- May 11, 2012
- Atif Zaman, MD, MPH
A compendium of information on how these protease inhibitors interact with other drugs often needed by patients with HCV infection
- Reviewing:
- Kiser JJ et al. Hepatology 2012 May; 55:1620
SUMMARY AND COMMENT
Eating Certain Fish Might Prevent Liver Cancer
- May 11, 2012
- Atif Zaman, MD, MPH
In a large prospective study in Japan, higher consumption of fish with n-3 polyunsaturated fatty acids translated to lower risk for hepatocellular carcinoma.
- Reviewing:
- Sawada N et al. Gastroenterology 2012 Feb 16
FEATURE
Difficulties and Differences on C. difficileFree
- May 11, 2012
An ID doc's take on the difficulties of treating C. difficile.
SUMMARY AND COMMENT
High Hepatitis B Surface Antigen Level Increases Risk for Hepatocellular Carcinoma
- May 4, 2012
- Atif Zaman, MD, MPH
The finding was for patients with a low hepatitis B virus DNA level.
- Reviewing:
- Tseng T-C et al. Gastroenterology 2012 May; 142:1140
SUMMARY AND COMMENT
New Tests Predict Clinical Outcomes in Chronic Hepatitis C VirusFree
- May 4, 2012
- Atif Zaman, MD, MPH
A battery of quantitative liver-function tests might provide a noninvasive method of risk assessment.
- Reviewing:
- Everson GT et al. Hepatology 2012 Apr; 55:1019
SUMMARY AND COMMENT
Catching More Cancer with Endoscopic Ultrasonography: Go FISH
- May 4, 2012
- Chris E. Forsmark, MD
Adding fluorescence in-situ hybridization to conventional cytology improved diagnostic accuracy of endoscopic ultrasound-guided fine-needle aspiration biopsy for malignancy.
- Reviewing:
- Levy MJ et al. Gastroenterology 2012 May; 142:1112
FEATURE
How Do You Treat Eosinophilic Esophagitis?Free
- May 4, 2012
With no consensus on a gold standard treatment, Dr. Brian Fennerty wants your feedback in his blog Gut Check.
SUMMARY AND COMMENT
Rabeprazole-Based Rescue Therapy for Helicobacter pylori Successful in Malaysia
- April 27, 2012
- David J. Bjorkman, MD, MSPH (HSA), SM (Epid.)
After PPI-based triple therapy failed, most infections were eradicated with rabeprazole and amoxicillin.
- Reviewing:
- Goh K-L et al. Aliment Pharmacol Ther 2012 May; 35:1097
Editor's Picks from across Journal Watch
SUMMARY AND COMMENT
Clot Risk Remains High in Medical Patients After Discharge
- April 30, 2012
- By Neil H. Winawer, MD, SFHM
- Hospital Medicine
A study of medically ill hospitalized patients revealed that more than half of venous thromboembolic events occurred after hospital discharge.
- Reviewing:
- J Hosp Med 2012 Mar; 7:231
SUMMARY AND COMMENT
Low-Dose vs. Standard-Dose CT for AppendicitisFree
- April 25, 2012
- By J. Stephen Bohan, MD, MS, FACP, FACEP
- Emergency Medicine
Low-dose computed tomography was noninferior to standard-dose CT for evaluating suspected appendicitis in nonobese young adults.
- Reviewing:
- N Engl J Med 2012 Apr 26; 366:1596
SUMMARY AND COMMENT
Long-Term Opioid Analgesic Use After Low-Risk Surgery May Be Common
- March 27, 2012
- By Thomas L. Schwenk, MD
- General Medicine
The likelihood of receiving an opioid prescription 1 year later was almost 50% greater if opioids had been prescribed postoperatively.
- Reviewing:
- Arch Intern Med 2012 Mar 12; 172:425
SUMMARY AND COMMENT
Estrogen Therapy and Breast Cancer Risk: More from the Women's Health InitiativeFree
- March 22, 2012
- By Andrew M. Kaunitz, MD
- Women's Health
Incidence of and mortality from breast cancer were clearly lower than in women who received placebo.
- Reviewing:
- Lancet Oncol 2012 Mar 7
Journal Watch Gastroenterology summarizes important medical journal articles about a wide variety of GI subjects including cirrhosis, dyspepsia, gastric cancer, GERD, H. pylori, and hepatitis.
