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Gastroenterology
Your concise source for authoritative clinical insight into the best and latest GI research.
Featured Article

SUMMARY AND COMMENT
Missed Opportunities to Detect Colorectal Cancer
- November 6, 2009
- Douglas K. Rex, MD
Prior opportunities for diagnostic evaluations were missed in nearly one third of patients with newly diagnosed CRC.
- Reviewing:
- Singh H et al. Am J Gastroenterol 2009 Oct; 104:2543
Recent Gastroenterology Articles
SUMMARY AND COMMENT
Thiopurines and Risk for Lymphoproliferative Disorders
- November 6, 2009
- Douglas K. Rex, MD
Patients with inflammatory bowel disease who received thiopurines had excess risk for LPDs.
- Reviewing:
- Beaugerie L et al. Lancet 2009 Oct 19
SUMMARY AND COMMENT
Trends in Uncomplicated Peptic Ulcer Disease
- November 6, 2009
- David J. Bjorkman, MD, MSPH (HSA), SM (Epid.)
Incidence in the U.K. declined by 50% during the last decade.
- Reviewing:
- Cai S et al. Aliment Pharmacol Ther 2009 Nov; 30:1039
SUMMARY AND COMMENT
Viramidine vs. Ribavirin for Hepatitis C Infection
- November 6, 2009
- Atif Zaman, MD, MPH
The ribavirin prodrug viramidine failed to demonstrate noninferiority to ribavirin in achieving sustained virologic response rates.
- Reviewing:
- Benhamou Y et al. Hepatology 2009 Sep; 50:717
SUMMARY AND COMMENT
MicroRNA Expression in Hepatocellular Cancer
- November 3, 2009
- David H. Ilson, MD, PhD
- Oncology and Hematology
Low expression of miR-26 seemed to affect survival and predict response to interferon.
- Reviewing:
- Ji J et al. N Engl J Med 2009 Oct 8; 361:1437
SUMMARY AND COMMENT
H. pylori and Gastric Cancer
- October 30, 2009
- David J. Bjorkman, MD, MSPH (HSA), SM (Epid.)
Eradication of H. pylori infection did not significantly reduce the incidence of gastric cancer.
- Reviewing:
- Mabe K et al. World J Gastroenterol 2009 Sep 14; 15:4290
SUMMARY AND COMMENT
Does Infliximab Reduce Colectomies in Ulcerative Colitis?
- October 30, 2009
- Douglas K. Rex, MD
Patients who received infliximab achieved significantly lower rates of colectomies than those who received placebo.
- Reviewing:
- Sandborn WJ et al. Gastroenterology 2009 Oct; 137:1250
SUMMARY AND COMMENT
Is Breast-Feeding Safe for Women with Inflammatory Bowel Disease?
- October 30, 2009
- Douglas K. Rex, MD
Breast-feeding was not associated with excess risk for disease flare during the postpartum year.
- Reviewing:
- Moffatt DC et al. Am J Gastroenterol 2009 Oct; 104:2517
SUMMARY AND COMMENT
Appendectomy as Treatment for Ulcerative Proctitis?
- October 30, 2009
- Douglas K. Rex, MD
In an uncontrolled trial, appendectomy seemed to reduce ulcerative proctitis symptoms.
- Reviewing:
- Bolin TD et al. Am J Gastroenterol 2009 Oct; 104:2476
SUMMARY AND COMMENT
Radiation Exposure from Medical Imaging Procedures
- October 23, 2009
- David A. Johnson, MD
More than 2% of patients in a population-based study were exposed to high or very high annual effective doses of ionizing radiation.
- Reviewing:
- Fazel R et al. N Engl J Med 2009 Aug 27; 361:849
SUMMARY AND COMMENT
Mortality Risk in Celiac Disease
- October 23, 2009
- Douglas K. Rex, MD
Villous atrophy, intraepithelial lymphocytosis, and latent celiac disease were all associated with excess mortality.
- Reviewing:
- Ludvigsson JF et al. JAMA 2009 Sep 16; 302:1171
Editor's Picks from across Journal Watch
SUMMARY AND COMMENT
New Retrovirus Is Associated with Chronic Fatigue SyndromeFree
- October 22, 2009
- By Anthony L. Komaroff, MD
- General Medicine
Could a human retrovirus be one cause of CFS? CME
- Reviewing:
- Science 2009 Oct 8
SUMMARY AND COMMENT
Treatment of Localized Prostate Cancer in the Era of PSA Screening
- October 15, 2009
- By Thomas L. Schwenk, MD
- General Medicine
Watchful waiting is appropriate in older men with localized cancers. Interview
- Reviewing:
- JAMA 2009 Sep 16; 302:1202
SUMMARY AND COMMENT
Sunscreen for Organ Transplant Recipients
- October 23, 2009
- By Craig A. Elmets, MD
- Dermatology
An ounce of sunscreen is worth a pound of cure.
- Reviewing:
- Br J Dermatol 2009 Nov; 161:78
SUMMARY AND COMMENT
Surgical Masks or N95 Respirators for the Flu?Free
- October 21, 2009
- By Richard T. Ellison III, MD
- Infectious Diseases
In a randomized trial, surgical masks and N95 respirators provided healthcare workers with comparable protection against influenza.
- Reviewing:
- JAMA 2009 Oct 1
Journal Watch Gastroenterology summarizes important medical journal articles about a wide variety of GI subjects including cirrhosis, dyspepsia, gastric cancer, GERD, H. pylori, and hepatitis.
