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Gastroenterology
Journal Watch condenses summaries of key research across specialties from more than 250 medical journals into concise yet comprehensive articles, incorporating clinical commentary from prominent physician-editors in the field.
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Featured Article
SUMMARY AND COMMENT
Cancer Risk Increased in Relatives of Patients with Serrated Polyposis
- May 11, 2012
- Douglas K. Rex, MD
Findings support evidence for an inherited component to the disease.
- Reviewing:
- Win AK et al. Am J Gastroenterol 2012 May; 107:770
Recent Gastroenterology Articles
SUMMARY AND COMMENT
A Review of Drug Interactions of Telaprevir and Boceprevir
- May 11, 2012
- Atif Zaman, MD, MPH
A compendium of information on how these protease inhibitors interact with other drugs often needed by patients with HCV infection
- Reviewing:
- Kiser JJ et al. Hepatology 2012 May; 55:1620
SUMMARY AND COMMENT
Eating Certain Fish Might Prevent Liver Cancer
- May 11, 2012
- Atif Zaman, MD, MPH
In a large prospective study in Japan, higher consumption of fish with n-3 polyunsaturated fatty acids translated to lower risk for hepatocellular carcinoma.
- Reviewing:
- Sawada N et al. Gastroenterology 2012 Feb 16
FEATURE
Difficulties and Differences on C. difficileFree
- May 11, 2012
An ID doc's take on the difficulties of treating C. difficile.
SUMMARY AND COMMENT
High Hepatitis B Surface Antigen Level Increases Risk for Hepatocellular Carcinoma
- May 4, 2012
- Atif Zaman, MD, MPH
The finding was for patients with a low hepatitis B virus DNA level.
- Reviewing:
- Tseng T-C et al. Gastroenterology 2012 May; 142:1140
SUMMARY AND COMMENT
New Tests Predict Clinical Outcomes in Chronic Hepatitis C VirusFree
- May 4, 2012
- Atif Zaman, MD, MPH
A battery of quantitative liver-function tests might provide a noninvasive method of risk assessment.
- Reviewing:
- Everson GT et al. Hepatology 2012 Apr; 55:1019
SUMMARY AND COMMENT
Catching More Cancer with Endoscopic Ultrasonography: Go FISH
- May 4, 2012
- Chris E. Forsmark, MD
Adding fluorescence in-situ hybridization to conventional cytology improved diagnostic accuracy of endoscopic ultrasound-guided fine-needle aspiration biopsy for malignancy.
- Reviewing:
- Levy MJ et al. Gastroenterology 2012 May; 142:1112
FEATURE
How Do You Treat Eosinophilic Esophagitis?Free
- May 4, 2012
With no consensus on a gold standard treatment, Dr. Brian Fennerty wants your feedback in his blog Gut Check.
SUMMARY AND COMMENT
Rabeprazole-Based Rescue Therapy for Helicobacter pylori Successful in Malaysia
- April 27, 2012
- David J. Bjorkman, MD, MSPH (HSA), SM (Epid.)
After PPI-based triple therapy failed, most infections were eradicated with rabeprazole and amoxicillin.
- Reviewing:
- Goh K-L et al. Aliment Pharmacol Ther 2012 May; 35:1097
SUMMARY AND COMMENT
Prenatal PPI Exposure and Childhood Asthma
- April 27, 2012
- David J. Bjorkman, MD, MSPH (HSA), SM (Epid.)
Maternal PPI use during pregnancy or the year thereafter is associated with an increased risk for asthma in the offspring but may not be causal. CME
- Reviewing:
- Andersen ABT et al. Aliment Pharmacol Ther 2012 May; 35:1190
SUMMARY AND COMMENT
The Higher the Body-Mass Index, the Higher the Risk for Adenoma
- April 27, 2012
- Douglas K. Rex, MD
A 5-unit increase in BMI was associated with a 19% increased risk for colorectal adenoma. CME
- Reviewing:
- Ben Q et al. Gastroenterology 2012 Apr; 142:762
Editor's Picks from across Journal Watch
SUMMARY AND COMMENT
Low-Dose vs. Standard-Dose CT for AppendicitisFree
- April 25, 2012
- By J. Stephen Bohan, MD, MS, FACP, FACEP
- Emergency Medicine
Low-dose computed tomography was noninferior to standard-dose CT for evaluating suspected appendicitis in nonobese young adults.
- Reviewing:
- N Engl J Med 2012 Apr 26; 366:1596
SUMMARY AND COMMENT
Long-Term Opioid Analgesic Use After Low-Risk Surgery May Be Common
- March 27, 2012
- By Thomas L. Schwenk, MD
- General Medicine
The likelihood of receiving an opioid prescription 1 year later was almost 50% greater if opioids had been prescribed postoperatively.
- Reviewing:
- Arch Intern Med 2012 Mar 12; 172:425
SUMMARY AND COMMENT
Estrogen Therapy and Breast Cancer Risk: More from the Women's Health InitiativeFree
- March 22, 2012
- By Andrew M. Kaunitz, MD
- Women's Health
Incidence of and mortality from breast cancer were clearly lower than in women who received placebo.
- Reviewing:
- Lancet Oncol 2012 Mar 7
SUMMARY AND COMMENT
A New Tool to Predict Delirium in ICU PatientsFree
- March 20, 2012
- By Vanja C. Douglas, MD
- Neurology
A new prediction rule can help identify critically ill patients at high risk for delirium.
- Reviewing:
- BMJ 2012 Feb 9; 344:e420
Journal Watch Gastroenterology summarizes important medical journal articles about a wide variety of GI subjects including cirrhosis, dyspepsia, gastric cancer, GERD, H. pylori, and hepatitis.
